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Gilead Sciences, Inc.

Healthcare · Drug Manufacturers - General · United States

$146.08
-0.03% today
Mkt Cap
$181.13B
P/E
N/A
Fwd P/E
14.77×
Div Yield
2.25%
Beta
0.336×
52W Range
77.0%
Company profileSource: provider

Gilead Sciences, Inc., a biopharmaceutical company, discovers, develops, and commercializes medicines in the areas of unmet medical need in the United States, Europe, and internationally. The company provides Biktarvy, Descovy, Genvoya, Odefsey, Sunlenca, Symtuza, and YeztugoFor the treatment of HIV-1 infection in patients. It also provides Epclusa, Livdelzi, and Vemlidy to treat chronic hepatitis C virus, primary biliary cholangitis, and chronic hepatitis B virus; Tecartus, a T-cell therapy for the treatment of adult patients; Trodelvy, an injection for intravenous use; and Yescarta, a suspension for intravenous infusion, is a CAR T-cell therapy for the treatment of adult patients. Further, it provides AmBisome, for the treatment of serious invasive fungal infections; and Veklury for the treatment of COVID-19. Additionally, the company engages in the development of various immunotherapies for patients with cancer and other incurable diseases. The company has collaboration agreements with Shenzhen Pregene Biopharma Co., Ltd.; Abingworth; Arcus Biosciences, Inc.; Merck Sharp & Dohme Corp.; Janssen Sciences Ireland Unlimited Company; Japan Tobacco, Inc.; Everest Medicines; Merck & Co, Inc.; Tentarix Biotherapeutics Inc.; and Assembly Biosciences, Inc. It also has research collaboration, option, and license agreement with Merus N.V. for the discovery of novel dual tumor-associated antigens (TAA) targeting trispecific antibodies. The company has a collaboration with Terray Therapeutics, Inc. to discover and develop small molecule therapies; and LEO Pharma to develop, manufacture, and commercialize the small molecule oral STAT6 program. The company was incorporated in 1987 and is headquartered in Foster City, California.

www.gilead.com
By the numbersComputed from live metrics

Shares trade at a moderate 17.9× trailing earnings, easing to 13.6× on forward estimates. Profitability shows a net margin of 31.0% and return on equity of 43.4%. Leverage is modest at 0.8× net debt/EBITDA. Revenue grew 4.4% year-on-year. It yields 2.5% in dividends. The mean analyst target of USD157.67 sits 20.1% above the current price (Buy, 27 analysts).

AI analysisAI-generated · 04 Jul 2026 · claude-opus (research)

business model

Gilead Sciences is a biopharmaceutical company focused on developing and commercializing therapies, with historic leadership in antiviral treatments for HIV and viral hepatitis, plus a growing oncology franchise. Revenue is concentrated in patented, high-value drugs sold globally. Growth depends on its HIV portfolio, pipeline advancement, and oncology diversification.

revenue segments

Gilead reports primarily as a single pharmaceutical business, with product revenue concentrated in HIV therapies (led by Biktarvy and the Descovy franchise, plus long-acting agents such as lenacapavir), liver disease (hepatitis B and C), and oncology (including cell therapy via Kite's Yescarta and Tecartus, and Trodelvy). HIV generates the majority of product sales.

key dependencies

The business depends on continued HIV market leadership and Biktarvy sales, successful launch and uptake of long-acting HIV prevention (lenacapavir), pipeline and oncology execution, patent protection and exclusivity timelines, regulatory approvals, and pricing and reimbursement dynamics.

competitors

Competitors include ViiV Healthcare (GSK-led) in HIV, AbbVie and others in hepatitis, and a broad set of oncology and cell-therapy players such as Bristol Myers Squibb, Novartis, Merck, and AstraZeneca. It also faces generic competition as patents expire.

moat

Gilead's moat rests on its dominant HIV franchise, patent-protected best-in-class therapies, deep antiviral R&D expertise, established prescriber and payer relationships, and long-acting product innovation that can extend franchise durability.

risks

Risks include HIV revenue concentration and eventual patent cliffs (Biktarvy loss of exclusivity), clinical and regulatory setbacks, uncertain returns on oncology and cell-therapy investments, drug-pricing reform and reimbursement pressure, and competition including from long-acting rivals.

01

Financials & metrics

as of 27 Aug 2026
52-week rangeNear 52-week high · 77%
Low $108.46Now $146.08High $157.29

Price is closer to the high end of its range. Green = nearer the yearly low, red = nearer the high — a position indicator, not a buy/sell signal.

Valuation
Profitability
Growth
Financial Health
Efficiency
Cash Flow
Per Share
Dividend
Market

Tap any metric for an explanation. provider computedN/A not available from source

Profit & loss · annual (USD)latest net margin 28.9%
📈

Valuation history is being recorded

We snapshot P/E and price targets daily. This chart fills in over the coming days.

Full financial statements

Income statement

Line item20252024202320222021
Total revenue$29.44B$28.75B$27.12B$27.28B
Cost of revenue$6.23B$6.25B$6.50B$5.66B
Gross profit$23.21B$22.50B$20.62B$21.62B
Operating expense$11.51B$11.91B$11.78B$10.65B
R&D$5.80B$5.91B$5.72B$4.98B
Operating income$11.70B$10.60B$8.84B$10.97B
Interest expense$1.02B$977.00M$944.00M$935.00M
Pretax income$9.80B$690.00M$6.86B$5.81B
Tax provision$1.29B$211.00M$1.25B$1.25B
Net income$8.51B$480.00M$5.67B$4.59B
EBITDA$13.58B$4.43B$10.50B$8.85B
Diluted EPS$6.78$0.38$4.50$3.64

Balance sheet

Line item20252024202320222021
Total assets$59.02B$58.99B$62.13B$63.17B
Current assets$18.34B$19.17B$16.09B$14.44B
Cash & equivalents$7.56B$9.99B$6.08B$5.41B
Inventory$1.77B$1.71B$1.79B$1.51B
Total liabilities$36.41B$39.75B$39.38B$41.96B
Current liabilities$11.81B$12.00B$11.28B$11.24B
Total debt$24.94B$26.71B$24.99B$25.23B
Long-term debt$22.13B$24.90B$23.19B$22.96B
Shareholders' equity$22.70B$19.33B$22.83B$21.24B
Retained earnings$13.73B$11.50B$16.30B$15.69B
Working capital$6.53B$7.17B$4.80B$3.21B

Cash flow

Line item20252024202320222021
Operating cash flow$10.02B$10.83B$8.01B$9.07B
Investing cash flow-$4.79B-$3.45B-$2.27B-$2.47B
Financing cash flow-$7.75B-$3.43B-$5.13B-$6.47B
Capital expenditure-$563.00M-$523.00M-$585.00M-$728.00M
Free cash flow$9.46B$10.30B$7.42B$8.34B
Dividends paid-$4.00B-$3.92B-$3.81B-$3.71B
Share buybacks-$1.92B-$1.15B-$1.00B-$1.40B
End cash position$7.56B$9.99B$6.08B$5.41B

Reported figures from public filings via Yahoo Finance. Line coverage varies by company. Not investment advice.

02

Dividends

Dividend Yield
2.25%
Annual Rate
$3.28
Payout Ratio
43.4%
Frequency
Quarterly
Upcoming ex-date
15 Sept 2026
Pay date
29 Sept 2026
Most recent
$0.82
Dividend history · per payment (USD)
03

Analyst assessment

as of 27 Aug 2026
Buy27 analysts
Implied to mean target
+7.8%
Low $123.00High $180.00
Now
$146.08
Low
$123.00
Mean
$157.41
High
$180.00
Rating distribution
Strong Buy 6
Buy 16
Hold 7
Sell 0
Strong Sell 0

Aggregate consensus only. Named per-analyst targets require a premium source and are not shown; the data model is ready to hold them if one is added.

04

Technicals

as of 26 Aug 2026
CloseSMA 50SMA 200Death cross
SMA 50
$133.04
SMA 200
$133.38
RSI (14)
89.5
MACD
4.43
RSI (14) · overbought > 70 · oversold < 30
05

News

Gilead’s Core Business Is Accelerating, But Will Its $11 Billion Pipeline Bet Pay Off?
Gilead Sciences, Inc. (NASDAQ:GILD) produced an unusual earnings report in fiscal Q2 2026. Its commercial portfolio delivered double-digit growth, and yet the company posted one of the largest quarterly losses in its recent history. So where did the disconnect come from? It was created by more than $11 billion in acquired research and development expenses […]
Insider Monkey · 5d ago
Read ↗
Gilead’s HIV Business is Surging, but is the Company Too Dependent on One Franchise?
Gilead Sciences, Inc. (NASDAQ:GILD) delivered strong fiscal Q2 2026 results, with total revenue rising 10% year over year to approximately $7.8 billion. The performance was primarily driven by continued growth across its HIV franchise, including Biktarvy and the newly launched Yeztugo. Gilead also raised its full-year product-sales guidance following the quarter. However, HIV products generated […]
Insider Monkey · 5d ago
Read ↗
Gilead’s Revenue Is Accelerating, But are its Acquisitions Worth the Cost?
Gilead Sciences, Inc. (NASDAQ:GILD) delivered its strongest commercial momentum in several years during fiscal Q2 2026, with growth extending across HIV, oncology, and liver disease. Total revenue increased 10% year over year to approximately $7.8 billion, while product sales rose 8% to $7.6 billion. Yet, the income statement tells a considerably less flattering story. Gilead […]
Insider Monkey · 5d ago
Read ↗
Pfizer vs. Gilead: Which Drugmaker Has the Stronger Growth Story?
The next few years will test whether Pfizer Inc. (NYSE:PFE) can replace yesterday’s blockbusters, and whether Gilead Sciences, Inc. (NASDAQ:GILD) can become more than an HIV company. Pfizer’s (NYSE:PFE) newer medicines are gaining traction, but that growth has yet to accelerate the wider business. Gilead (NASDAQ:GILD) is expanding faster, although its performance remains concentrated in […]
Insider Monkey · 5d ago
Read ↗
Making Drugs With AI: Biopharma Giants Gear Up For New Arena
The biggest names behind biotech stocks are investing richly in artificial intelligence with the goal of speeding up drug development.
Investor's Business Daily · 7d ago
Read ↗
Does Gilead (GILD) Pairing With Nucleai Reveal a Deeper Shift in Its Oncology Strategy?
In August 2026, Nucleai announced an ongoing translational research collaboration with Gilead Sciences, using AI-powered tissue analytics to support Gilead's global antibody-drug conjugate clinical development programs across multiple oncology indications. The partnership highlights how integrating AI-native computational pathology with clinical outcomes may help standardize biomarker assessment and refine precision medicine efforts in Gilead's oncology portfolio. Next, we'll examine how...
Simply Wall St. · 8d ago
Read ↗
Worried About a Market Crash? These 3 Stocks Beat the S&P 500 in 2008 and 2022
These stocks can be safe-haven investments to hide out in amid market turmoil.
Motley Fool · 9d ago
Read ↗
Biotech Stocks Are Booming. What This Top Fund Is Buying Now.
Franklin Biotechnology Discovery has a much higher 13% five-year annualized return than a biotech index ETF’s 5.3%
Barrons.com · 9d ago
Read ↗
Is Gilead's Expanding HIV Portfolio a Growth Catalyst?
Gilead's HIV franchise gains momentum as Yeztugo ramps up, Biktarvy leads treatment and new pipeline advances strengthen growth prospects.
Zacks · 10d ago
Read ↗
Gilead Sciences Has Quietly Become One of the Most Underrated Turnaround Stories in Healthcare. Here's Why Wall Street Is Excited.
The company's HIV franchise is stronger than ever, and it's adding a stable of oncology drugs.
Motley Fool · 10d ago
Read ↗
Gilead yanks out a thorn in its side in major court ruling
A federal appeals court just handed Gilead Sciences (GILD) a legal win that extends into the company's revenue. The decision blocks a group of companies from importing cheaper foreign versions of Gilead's top HIV drug and selling them to American patients. For a company that relies heavily on a ...
TheStreet · 11d ago
Read ↗
Gilead Sciences (GILD): Buy, Sell, or Hold Post Q2 Earnings?
Over the last six months, Gilead Sciences’s shares have sunk to $137.77, producing a disappointing 11.3% loss - a stark contrast to the S&P 500’s 13.1% gain. This might have investors contemplating their next move.
StockStory · 12d ago
Read ↗
Can MacroGenics (MGNX) Turn Gilead Sciences (GILD)’s $10M Milestone Into a Major Pipeline Catalyst?
On August 11, Gilead Sciences, Inc. (NASDAQ:GILD) exercised its option to exclusively license a preclinical bispecific program targeting solid tumors using MacroGenics, Inc. (NASDAQ:MGNX)’s proprietary TRIDENT platform. The decision triggered a $10 million milestone payment to MacroGenics, injecting momentum into the companies’ 2022 collaboration. That broader agreement spans three programs, including clinical-stage CD123 x CD3 […]
Insider Monkey · 14d ago
Read ↗
Gilead wins appeals court ruling against overseas drug imports
A federal appeals court ruled Thursday that international versions of Gilead's HIV drug Biktarvy differ materially from FDA-regulated U.S. versions
Quartz · 14d ago
Read ↗
Key HIV stat over 70% leaves BofA siding with Gilead
Gilead Sciences (GILD) closed a strong second quarter, and Wall Street noticed. The drugmaker beat sales expectations across its biggest franchises, raised its full-year outlook, and gave analysts fresh reasons to stay bullish heading into the back half of 2026. Bank of America was one of them. The ...
TheStreet · 20d ago
Read ↗
What Insmed Stock's Premium Is Actually Buying
Management has just raised the peak-sales estimate, and a large slice of it belongs to a drug still running Phase III trials.
Trefis · 21d ago
Read ↗
GILD Q2 Earnings Call Raises Outlook on HIV and PrEP Strength
Gilead raises its 2026 base-business outlook as HIV and PrEP momentum strengthens, while Trodelvy growth and two potential launches shape the second half.
Zacks · 21d ago
Read ↗
KYMR Q2 Earnings and Revenues Top Estimates on Gilead, Sanofi Payments
Kymera Therapeutics beat revenue estimates as milestone payments boost results and advances KT-621 development, with key trial data expected by year-end.
Zacks · 22d ago
Read ↗
MSD and Gilead scrap Phase III Trodelvy-Keytruda study on lacklustre interim data
This study miss marks a setback for Gilead’s Trodelvy expansion plans, which include both mono and combination therapy approaches.
Clinical Trials Arena · 22d ago
Read ↗
Gilead Slumps As Long-Term Uncertainty Clouds Massive HIV Beat
Gilead Sciences narrowly beat sales expectations for its HIV PrEP drug, Yeztugo. Gilead stock slipped, still in a downtrend.
Investor's Business Daily · 23d ago
Read ↗
06

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07

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